Maleic anhydride is used in the formulation of resins. MCA [1974]. MATERIAL SAFETY DATA SHEET MALEIC ANHYDRIDE 1. Maleic anhydride released into water will hydrolyze rapidly (half-life 0.37 min) to maleic acid. Ingestion: OSHA Vacated PELs: Acetic anhydride: No OSHA Vacated PELs are listed for this chemical. Chronic: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in … Wash out mouth with water. Maleic anhydride CAS -No. Rinse mouth with water (only if the person is conscious). You will be subject to the destination website's privacy policy when you follow the link. Eye: Acute (short-term) inhalation exposure of humans to maleic anhydride has been observed to cause irritation of the respiratory tract and eye irritation. EC -No. Maleic anhydride has several uses, almost all of them related to the synthesis of other chemicals as fumaric and tartaric acids, certain agricultural chemicals (i.e., maleic hydrazide, malathion), lubricants, surface active agents, resins in different products, dye intermediates, pharmaceuticals, and more. Anhydrides. Safety Statements :26-36/37/39 Consult a physician. May cause conjunctivitis. Symptoms and effects are not known to date. Moisture sensitive. National Cancer Institute, June 17, 1974. pain. The anhydride of maleic acid has five atoms in its cyclic molecule, the unsaturated bond undergoes free radical polymerization in the presence of an initiator. Saving Lives, Protecting People, The National Institute for Occupational Safety and Health (NIOSH), National Institute for Occupational Safety and Health, A – NIOSH Potential Occupational Carcinogens, E – OSHA Respirator Requirements for Selected Chemicals, G – 1989 Air Contaminants Update Project: Exposure Limits NOT in Effect, Type C & CE – Definitions for Type C and Type CE Respirators, U.S. Department of Health & Human Services. Common Name Maleic Anhydride Synonym(s) 2,5Furandione Formula C 4 H 2 O 3 CAS Number 108316 COMPONENT CAS NUMBER CONCENTRATION Maleic Anhydride 108316 ≤ Section 4. Inhalation: exposure may cause allergic respiratory reaction (asthma). First-aid measures General Advice Show this safety data sheet to the doctor in attendance. 6. Maleic Anhydride Flinn Scientific, Inc. P.O. Product Safety Assessment: Maleic Anhydride Last Revised: August 2015 Page 2 of 3 Potential Human Health Effects Occupational Exposure Potential for occupational exposure to Maleic Anhydride exists during manufacture, at transloading, storage and staging areas, and during mixing and sampling operations in the manufacture of other products. Evaporate the chloroform in a hood. Causes respiratory Click here for information on selection of N, R, or P filters.Any appropriate escape-type, self-contained breathing apparatus, Important additional information about respirator selection, cis-Butenedioic anhydride, 2,5-Furanedione, Maleic acid anhydride, Toxilic anhydride. Box 219, Batavia, IL 60510 (800) 452-1261 Chemtrec Emergency Phone Number: (800) 424-9974 Maleic Anhydride Safety Data Sheet International Diol Company SAFETY DATA SHEET according to Regulation (EC) No. May cause allergic skin and respiratory reaction. The odour warning when the exposure limit value is exceeded is insufficient. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. May cause skin sensitization, an allergic ... Maleic anhydride is transported also as hot liquid (70°C); contact of the skin should be avoided. Product name : Maleic Anhydride CAS-No. Interagency Collaborative Group on Environmental Carcinogens. Target Organs: Lungs, respiratory system, eyes, : 108-31-6 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratory chemicals, Manufacture of substances 1.3 Details of the supplier of the safety data sheet (2) Maleic anhydride has an acrid odor, with an odor threshold of 0.32 parts per million (ppm). 5. Product name : Maleic anhydride Product Number : 63200 Brand : Sigma-Aldrich Index-No. MALEIC ACID page 2 of 6 This Fact Sheet is a summary source of information of all ... (as Maleic Anhydride) exists, use a MSHA/NIOSH approved self-contained breathing apparatus with a full facepiece operated in a … "Maleic Anhydride, Maleic Acid, and Fumaric Acid." reaction, which becomes evident upon re-exposure to this material. Danger! Do NOT induce vomiting. Repeated Environmental: Maleic anhydride's fate in soil is unknown. ], inhalation, ingestion, skin and/or eye contact, irritation nose, upper respiratory system; conjunctivitis; photophobia (abnormal visual intolerance to light), double vision; bronchial asthma; dermatitis, Centers for Disease Control and Prevention. FIRST AID MEASURES General advice Consult a physician. : 108-31-6 Molecular Weight: 98.06 Chemical Formula: C4H2O3 Company: ADDTEK CHEMICAL SHANGHAI CO LTD TEL: +86 21 63352916 FAX: +86 21 51010033EXT8839 Causes chemical burns to the respiratory tract. Chem., 1979, 179, C19], and is considered an excellent dieneophile for Diels-Alder reactions [Felthouse, Timothy R. et al. First Aid Measures Description of Firstaid Measures General Advice: Consult a physician. Maleic anhydride, polymers Safety Profile. Causes redness and May cause digestive tract Substance Any concentration shown as a range is to protect confidentiality or is due to batch variation. tract irritation and possible burns. Exposure to high fume concentrations cause photophobia, Product Identification Synonyms: cis-Butenedioic anhydride; 2,5-furandione; toxilic anhydride CAS No. (5,8) The vapor pressure for maleic anhydride is 0.1 to 0.2 mm Hg at 25 °C. (2) Conversion Factors: A poison by intravenous route. Causes gastrointestinal tract burns. Polynt Group produces a great variety of anhydrides, but the most important ones are: Phthalic Anhydrides, Maleic Anhydride, Trimellitic Anhydride Maleic anhydride undergoes a potentially explosive exothermic Diels-Alder reaction with 1-methylsilacyclopenta-2,4-diene at 150C [Barton, T. J., J. Organomet. SAFETY DATA SHEET (in accordance with Regulation (EU) 2015/830) 108120-Maleic anhydride Version: 3 Revision date: 19/04/2016 Page 2 of 9 Print date: 19/04/2016 -Continued on next page.- P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Histological examination revealed nephrosis which increased in severity with the dose above 100 mg/kg. Maleic anhydride in daily doses of 20, 40,100, 250 or 600 mg/kg body weight, fed for 90 days to groups of 15 rats of each sex, caused macroscopic changes in the kidneys: enlargement and pale yellow discoloration. Wear safety goggles or eye protection in combination with breathing protection if powder. Reproductive Toxicity: No data available Reproductive toxicity - Rat - Oral NCI [1974]. Harmful if swallowed. Skin: : 108-31-6 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratorychemicals, Industrial & for professional use only. Causes eye burns. Up to 10 mg/m3: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode£(APF = 50) Any self-contained breathing apparatus with a full facepiece(APF = 50) Any supplied-air respirator with a full facepiece, Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus, Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having an N100, R100, or P100 filter. Reproductive Toxicity - Rat - Oral maleic anhydride safety name: maleic anhydride is 0.1 to 0.2 mm Hg at °C... 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